METHOD FOR PRODUCING 3-ALKENYLCEPHEM COMPOUND

摘要

<P>PROBLEM TO BE SOLVED: To provide a method for producing 7-amino-3-[2-(4-methylthiazol-5-yl)vinyl]-3-cephem-4-carboxylic acid having a high Z-isomer content and reduced impurities. Ž<P>SOLUTION: The content of a compound represented by formula (2) or a salt thereof is increased by subjecting the salt of a compound represented by formula (1) to enzymatic reaction to perform the deprotection reaction of the 7-position amide bonding and bringing an aqueous solution of a compound represented by formula (3) into contact with activated carbon. Ž<P>COPYRIGHT: (C)2010,JPO&INPIT Ž