发明名称 COMPOSITION HAVING ENHANCED PHARMACOKINETIC CHARACTERISTICS
摘要 PROBLEM TO BE SOLVED: To provide a composition that improves pharmacokinetic characteristics of a therapeutic component. SOLUTION: There is provided a composition, including a therapeutic component and an efficacy enhancing component, that improves pharmacokinetic characteristics of the therapeutic component. The therapeutic component may includeα-2-adrenergic agonist, and the efficacy enhancing component may include a fatty acid. In one embodiment, the therapeutic component and the efficacy enhancing component form a complex. The efficacy enhancing component is selected from the group consisting of anionic polymers, saturated fatty acids, unsaturated fatty acids and mixtures thereof. Specifically, the efficacy enhancing component is linolenic acid, and the therapeutic component is brimonidine. COPYRIGHT: (C)2010,JPO&INPIT
申请公布号 JP2010132681(A) 申请公布日期 2010.06.17
申请号 JP20100018776 申请日期 2010.01.29
申请人 ALLERGAN INC 发明人 WOODWARD DAVID F;AMBRUS GYORGY
分类号 A61K45/00;A61K9/08;A61K31/498;A61K47/12;A61K47/48;A61P25/00;A61P27/02;A61P43/00 主分类号 A61K45/00
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