| 发明名称 |
MACROCYCLIC COMPOUNDS FOR INHIBITION OF TUMOR NECROSIS FACTOR ALPHA |
| 摘要 |
The invention provides macrocyclic compounds and methods for their synthesis and use. In particular, the invention provides macrocyclic compounds that modulate the activity of tumor necrosis factor alpha and/or are useful in the treatment of medical conditions, such as, rheumatoid arthritis, psoriasis, and asthma.
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| 申请公布号 |
US2010152099(A1) |
申请公布日期 |
2010.06.17 |
| 申请号 |
US20090544604 |
申请日期 |
2009.08.20 |
| 申请人 |
LEE JINBO;BOND JULIAN F;TERRETT NICHOLAS;FAVALORO JR FRANK G;WANG DANIEL;BRIGGS TIMOTHY F;SEIGAL BENJAMIN A;SUN WEI-CHUAN;HALE STEPHEN P |
发明人 |
LEE JINBO;BOND JULIAN F.;TERRETT NICHOLAS;FAVALORO, JR. FRANK G.;WANG DANIEL;BRIGGS TIMOTHY F.;SEIGAL BENJAMIN A.;SUN WEI-CHUAN;HALE STEPHEN P. |
| 分类号 |
A61K38/12;A61P1/00;A61P3/10;A61P19/02;A61P25/28;A61P35/00;C07K5/12 |
主分类号 |
A61K38/12 |
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