发明名称 |
Method of Depleting Regulatory T Cell |
摘要 |
The present invention relates to the method for depleting in vivo regulatory T cell, the method for suppressing IL-10 producing activity of regulatory T cell, the method for treating diseases in which pathologic conditions are deteriorated by regulatory T cell and the method for enhancing tumor immunity which comprises administering to a patient a monoclonal antibody which specifically binds to human CC chemokine 4 (CCR4) or the antibody fragment thereof.
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申请公布号 |
US2010150917(A1) |
申请公布日期 |
2010.06.17 |
申请号 |
US20090573689 |
申请日期 |
2009.10.05 |
申请人 |
KYOWA HAKKO KIRIN CO., LTD. |
发明人 |
UEDA RYUZO;SHITARA KENYA;AKINAGA SHIRO;NIWA RINPEI;KOIKE MASAMICHI |
分类号 |
A61K39/395 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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