PHARMACEUTICAL FORMULATION

摘要

The present invention provides a pharmaceutical formulation for mornings comprising: an immediate release compartment containing a dihydropyridine calcium channel blocker as a pharmacologically active ingredient, and a sustained release compartment containing an HMG-CoA reductase inhibitor as a pharmacologically active ingredient. The formulation of the present invention reduces side effects caused by interaction between drugs and is effective in treating and preventing hypertension and hyperlipidemia and cardiovascular diseases or metabolic syndrome caused thereby due to pharmacological synergism. Also, the formulation can enhance drug compliance.