摘要 |
PROBLEM TO BE SOLVED: To provide an azithromycin dosage form which has bioavailability analogical to an instantly dischargeable azithromycin with the same dose and has gastrointestinal side effect smaller than the bioavailability. SOLUTION: The azithromycin dosage form includes azithromycin multiparticles and an effective amount of an alkalizing agent. Preferably, the alkalizing agent includes an aluminum salt, a magnesium salt, a calcium salt, a bicarbonate, a phosphate, a metal hydroxide, a metal oxide, N-methylglucamine, arginine, an arginine salt, an amine, or a combination thereof. COPYRIGHT: (C)2010,JPO&INPIT
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