发明名称 SULFONIC ACID SALT COMPOUND OF 4-CARBAMOYL-5-HYDROXY-IMIDAZOLE DERIVATIVE
摘要 <p>The object is to provide a stable SM-108 derivative, which is effective as a carcinostatic agent, particularly an SM-108 derivative having good storage stability. An SM-108 compound having good storage stability can be produced by producing an organic sulfonic acid salt compound of SM-108. Further, a crystalline SM-108 compound containing a trace amount of an organic carboxylic acid can be produced by using an aqueous solution of the organic sulfonic acid salt of SM-108, and by adding an alkali metal salt of an organic carboxylic acid to the aqueous solution to neutralize the aqueous solution and then causing the crystal precipitation in the solution.</p>
申请公布号 EP2196460(A1) 申请公布日期 2010.06.16
申请号 EP20080830235 申请日期 2008.09.16
申请人 MBR CO., LTD.;KATO, NOBUO 发明人 KATO, NOBUO;HIGUCHI, YUSUKE;KONDO, CHIHIRO;SUNAGAWA, MAKOTO
分类号 C07D233/90;A61K31/4164;A61P35/00 主分类号 C07D233/90
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