<p>Provided are methods and compositions that enhance Nrf2 (SKN-1) activation of phase II detoxification or antioxidant enzyme transcription, comprising plant extracts (e.g., willow extracts) or active fractions thereof, as well as methods for identifying additional compounds that increase the Nrf2-regulation of those enzymes.</p>
申请公布号
EP2195032(A2)
申请公布日期
2010.06.16
申请号
EP20080799474
申请日期
2008.09.11
申请人
JOSLIN DIABETES CENTER, INC.;SUNSTAR INC.
发明人
BLACKWELL, T. KEITH;MATSUMOTO, MOTONOBU;MAKINO, TAKETOSHI;GOTO, MASASHI;ISHIKADO, ATSUSHI;MAEDA, MARIKO;AZECHI, SATOE
