发明名称 HEAVY CHAIN MUTANT LEADING TO IMPROVED IMMUNOGLOBULIN PRODUCTION
摘要 The current invention comprises a nucleic acid encoding the amino acid sequence of the C-terminal part of the CH3-domain of an immunoglobulin of the class IgA or IgG, or the C-terminal part of the CH4-domain of an immunoglobulin of the class IgE or IgM, wherein the glycine-lysine-dipeptide comprised in the amino acid sequence of the C-terminal part of the CH3- or CH4-domain is encoded by the nucleic acid ggaaaa, or the nucleic acid ggcaaa, or the nucleic acid gggaaa, or the nucleic acid gggaag, or the nucleic acid ggcaag, or the nucleic acid ggaaag.
申请公布号 IL201919(D0) 申请公布日期 2010.06.16
申请号 IL20090201919 申请日期 2009.11.04
申请人 F. HOFFMANN-LA ROCHE AG 发明人
分类号 C07K 主分类号 C07K
代理机构 代理人
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