发明名称 |
N - SUBSTITUTED PYRROLIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND USES THEREOF IN THE PREPARATION OF MEDICAMENTS FOR THE TREATMENT AND PROPHYLAXIS OF DIPEPTIDYL PEPTIDASE IV -ASSOCIATED DISEASES |
摘要 |
The present invention relates to compounds of formula (I) wherein R<SUP>1</SUP>, R<SUP>2</SUP>, and X are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with DPP IV, such as diabetes, particularly non-insulin dependent diabetes mellitus, and impaired glucose tolerance. |
申请公布号 |
IL161158(A) |
申请公布日期 |
2010.06.16 |
申请号 |
IL20040161158 |
申请日期 |
2004.03.29 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
|
分类号 |
A61K;A61K31/40;A61K31/401;A61K31/4025;A61K31/403;A61K31/404;A61K31/4045;A61K31/4155;A61K31/416;A61K31/4178;A61K31/4184;A61K31/4196;A61K31/422;A61K31/423;A61K31/4245;A61K31/427;A61K31/428;A61K31/437;A61K31/4439;A61K31/444;A61K31/454;A61K31/4709;A61K31/497;A61K31/506;A61K31/5355;A61P1/00;A61P1/04;A61P3/04;A61P3/10;C07D;C07D207/16;C07D401/12;C07D401/14;C07D403/12;C07D403/14;C07D409/14;C07D413/12;C07D413/14;C07D417/12;C07D417/14;C07D471/04;C07D513/04 |
主分类号 |
A61K |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|