发明名称 Composition for enzyme inhibition
摘要 Compositions comprising one or more practically insoluble proteasome inhibitors and a cyclodextrin, particularly a substituted cyclodextrin, substantially increase the solubility of these proteasome inhibitors and facilitate their administration. Such compositions optionally comprise a buffer. Methods of treatment using such compositions are also disclosed.
申请公布号 US7737112(B2) 申请公布日期 2010.06.15
申请号 US20050299265 申请日期 2005.12.07
申请人 ONYX THERAPEUTICS, INC. 发明人 LEWIS EVAN R.;HO MARK NGUYEN;FONSECA FABIANA N.
分类号 A61K38/02;C08B37/16 主分类号 A61K38/02
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