发明名称 |
Thiaminases and thiaminase genes for use in apoptotic therapies |
摘要 |
This disclosure describes methods for preparing and utilizing thiaminase and thiaminase genes to induce apoptosis in a selected group of vertebrate cells in vivo by reducing the level of thiamin in the cells. Emphasis is on methods for inducing apoptosis in cancer cells.
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申请公布号 |
US7736898(B1) |
申请公布日期 |
2010.06.15 |
申请号 |
US20000675509 |
申请日期 |
2000.09.29 |
申请人 |
BRANDEIS UNIVERSITY |
发明人 |
FULTON CHANDLER;LAI ELAINE Y. |
分类号 |
C12N15/74;A01N63/00;A61K48/00;C07H21/02;C12N5/00;C12N5/02;C12N15/00 |
主分类号 |
C12N15/74 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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