发明名称 CETP inhibitors
摘要 Compounds of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compounds of Formula 1, A1 and A2 are each an aromatic ring, a 5-6-membered heterocyclic ring, an aromatic ring fused to a heterocyclic ring, a phenyl ring fused to a heterocyclic ring, or a cycloalkyl ring.
申请公布号 US7737295(B2) 申请公布日期 2010.06.15
申请号 US20050578694 申请日期 2005.04.08
申请人 MERCK SHARP & DOHME CORP. 发明人 ALI AMJAD;BOHN JOANN;DENG QIAOLIN;LU ZHIJIAN;SINCLAIR PETER J.;TAYLOR GAYLE E.;THOMPSON CHRISTOPHER F.;QURAISHI NAZIA
分类号 C07C261/00;A01N47/10;C07C205/00;C07C211/00;C07C229/00;C07C233/18;C07C271/16;C07C271/20;C07C271/22;C07C279/08;C07C311/04;C07C311/08;C07C317/32;C07D209/08;C07D213/40;C07D213/64;C07D213/65;C07D213/68;C07D213/89;C07D215/12;C07D215/26;C07D217/02;C07D217/14;C07D261/08;C07D271/06;C07D307/52;C07D307/79;C07D333/20;C07D333/22;C07D333/28 主分类号 C07C261/00
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