发明名称 SUBSTITUTED 1-PROPIOLYLPIPERAZINES HAVING AN AFFINITY FOR THE MGLUR5 RECEPTOR IN ORDER TO TREAT PAINFUL CONDITIONS
摘要 Substituted 1-propiolylpiperazine compounds corresponding to formula I in which X denotes N or C-R<SUP>2</SUP>, and n is an integer from 0 to 8, a method for producing such substituted 1-propiolylpiperazine compounds, pharmaceutical compositions containing such substituted 1-propiolylpiperazine compounds, and the use of such substituted 1-propiolylpiperazine compounds for modulating mGluR5 receptor activity or for treating or inhibiting pain and various other conditions, especially conditions at least partly mediated by the mGluR5 receptor.
申请公布号 PT1765816(E) 申请公布日期 2010.06.14
申请号 PT20050756539T 申请日期 2005.07.05
申请人 GRUENENTHAL GMBH 发明人 MICHAEL HAURAND;STEFAN OBERBOERSCH;RUTH JOSTOCK;SVEN KUEHNERT;RUTH JOSTOCK
分类号 C07D417/04;A61K31/495;A61P25/22 主分类号 C07D417/04
代理机构 代理人
主权项
地址