METHOD FOR PREPARING ROCURONIUM BROMIDE

摘要

PURPOSE: A method for preparing high quality and high purity rocuronium bromide is provided, which is industrially useful. CONSTITUTION: A method for preparing rocuronium bromide comprises the steps of: obtaining the compound of the chemical formula V by reacting the compound of IV with morpholine; obtaining the compound of the chemical formula VI by reacting the compound of the chemical formula V with an acetate compound; obtaining a compound of the chemical formula VII by reacting the compound of the chemical formula VI with pyrrolidine; and obtaining the compound of the chemical formula VIII by reacting the compound of the chemical formula VII with acetyl chloride.