发明名称 |
Preparation of functional gel particles with a dual crosslink network |
摘要 |
Functional gel particle formed from a crosslinked polymeric network including a fraction of stable crosslinks and a second fraction of cleavable crosslinks are disclosed. Functional compounds may be chemically or physically encapsulated within and/or released from the gel particle by selective cleavage of the cleavable crosslinks. The functional compounds may be delivered and released to a pre-selected target site. Peripheral or other accessible functionality on the surface of the gel particle allows attachment of a surface reactive agent, thereby modifying one or more surface properties of the gel particle. Processes of preparing the gel particles and processes of delivering the functional compounds to a target site are also disclosed.
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申请公布号 |
US2010143286(A1) |
申请公布日期 |
2010.06.10 |
申请号 |
US20070311673 |
申请日期 |
2007.10.09 |
申请人 |
CARNEGIE MELLON UNIVERSITY |
发明人 |
MATYJASZEWSKI KRZYSTOF;MIN KE;OH JUNG KWON;SPANSWICK JAMES;TSAREVSKY NICOLAY V. |
分类号 |
A61K31/74;A61K8/72;C08K11/00 |
主分类号 |
A61K31/74 |
代理机构 |
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地址 |
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