<p>The present invention provides imidazooxazole and imidazothiazole compounds and their syntheses. The compounds of the present invention are capable of inhibiting the activity of RAF kinase, such as B-RAF V600E. The compounds are useful for the treatment of cell proliferative disorders such as cancer.</p>
申请公布号
WO2010065893(A1)
申请公布日期
2010.06.10
申请号
WO2009US66826
申请日期
2009.12.04
申请人
ARQULE, INC.;LAPIERRE, JEAN-MARC;LIU, YANBIN;TANDON, MANISH;ASHWELL, MARK, A.
发明人
LAPIERRE, JEAN-MARC;LIU, YANBIN;TANDON, MANISH;ASHWELL, MARK, A.
