发明名称 |
SOLID DOSAGE FORMS OF BENDAMUSTINE |
摘要 |
In the present invention there is provided a pharmaceutical composition in a solid dosage form suitable for oral administration, the composition comprising bendamustine or a pharmaceutically acceptable ester, salt or solvate thereof as an active ingredient, and at least one pharmaceutically acceptable excipient, which is a pharmaceutically acceptable saccharide selected from the group consisting of one or more of a monosaccharide, a disaccharide, an oligosaccharide, a cyclic oligosaccharide, a polysaccharide and a saccharide alcohol, wherein the ratio by weight of the active ingredient to the saccharide excipient(s) is in the range of 1 :1-5. |
申请公布号 |
CA2745509(A1) |
申请公布日期 |
2010.06.10 |
申请号 |
CA20092745509 |
申请日期 |
2009.12.03 |
申请人 |
ASTELLAS DEUTSCHLAND GMBH |
发明人 |
COLLEDGE, JEFF;PROFITLICH, THOMAS ALFRED;PATZAK, ULRICH;QUATAS, TAOUFIK;OLTHOFF, MARGARETHA |
分类号 |
A61K9/20;A61K9/28;A61K31/4184 |
主分类号 |
A61K9/20 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|