摘要 |
PROBLEM TO BE SOLVED: To provide a production method for efficiently obtaining methyl 2-bromo-3-ä4-[2-(5-ethyl-2-pyridyl)ethoxy]phenyl}propionate with high efficiency and purity. SOLUTION: The method for producing 2-bromo-3-ä4-[2-(5-ethyl-2-pyridyl)ethoxy]phenyl}propionate with high purity includes: producing a solution containing a diazonium salt by reacting 4-[2-(5-ethyl-2-pyridyl)ethoxy]aniline with a nitrite in the presence of hydrobromic acid; reacting the diazonium salt with methyl acrylate in the presence of a copper catalyst; and washing a crude reaction product with hydrobromic acid. COPYRIGHT: (C)2010,JPO&INPIT
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