发明名称 TECHNETIUM- AND RHENIUM-BIS (HETEROARYL) COMPLEXES AND METHODS OF USE THEREOF FOR INHIBITING PSMA
摘要 A compound of Formula (I), a pharmaceutically acceptable salt, or solvate thereof, complexes with metals such as rhenium, technetium, and others to provide a complex for imaging tissues or treating disease, particularly where the metal is radioactive. Such complexes are specific to PSMA protein and can therefore be used in imaging or treating cancer of the prostate and other tissue where the protein is expressed.
申请公布号 CA2745955(A1) 申请公布日期 2010.06.10
申请号 CA20092745955 申请日期 2009.12.04
申请人 MOLECULAR INSIGHT PHARMACEUTICALS, INC. 发明人 BABICH, JOHN W.;ZIMMERMAN, CRAIG;JOYAL, JOHN;MARESCA, KEVIN P.;LU, GENLIANG;HILLIER, SHAWN
分类号 C07D213/38;A61K51/04;A61K51/08;C07C275/24 主分类号 C07D213/38
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