发明名称 |
6-CYCLOAMINO-3-(1H-PYRROLO[2,3-B]PYRIDIN-4-YL)IMIDAZO[1,2-B]PYRIDAZINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF |
摘要 |
<p>The invention relates to 6-cycloamino-3-(1H-pyrrolo[2,3-b]pyridin-4-yl)imidazo[1,2-b]pyridazine derivatives corresponding to the general formula (I) in which R2 represents an aryl group optionally substituted with one or more halogen atoms or C1-6-alkyl, C1-6-alkyloxy, C1-6-alkylthio, C1-6-fluoroalkyl, C1-6-fluoroalkyloxy and -CN groups or R2 represents a group chosen from C1-6-alkyl, C1-6-fluoroalkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-C1-6-alkyl groups; A represents a C1-7-alkylene group; B represents a C1-7-alkylene group; L represents either a nitrogen atom optionally substituted with an Rc or Rd group, or a carbon atom substituted with an Re1 group and an Rd group or two Re2 groups; the carbon atoms of A and of B being optionally substituted with one or more Rf groups, which may be identical to or different from one another. Preparation process and therapeutic use.</p> |
申请公布号 |
WO2010063929(A1) |
申请公布日期 |
2010.06.10 |
申请号 |
WO2009FR52336 |
申请日期 |
2009.11.30 |
申请人 |
SANOFI-AVENTIS;PACAUD, CHRISTOPHE;PUECH, FREDERIC |
发明人 |
PACAUD, CHRISTOPHE;PUECH, FREDERIC |
分类号 |
C07D519/00 |
主分类号 |
C07D519/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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