| 摘要 |
FIELD: medicine. ^ SUBSTANCE: claimed invention relates to field of medicine and pharmacology, namely to obtaining medication for peroral introduction. Claimed medication contains agglomerate of hard particles based on at least one excipient, where said agglomerate contains cyclooxigenase-2 inhibitor, corresponding to compounds of general formula or salts or solvates of such compounds, and at least one hydrophilic polymer, said agglomerate containing product of sputtering on said particles of solution or suspension of finely-grid grains of said inhibitor in said one or several polymers for agglomeration of said particles. Also claimed is method of obtaining said medication. Where R1, R2, R3, X and Y are given in the invention formula. ^ EFFECT: invention results in obtaining medication for peroral introduction. ^ 28 cl, 1 tbl, 7 ex |
