| 发明名称 |
Pyrimidinones as Casein Kinase II (CK2) Modulators |
| 摘要 |
A compound having Formula I: or a pharmaceutically acceptable salt thereof, wherein X, R, R and R are as defined in the specification; pharmaceutical compositions thereof; and methods of use thereof. The compounds of Formula I are inhibitors of Casein kinase II (CK2) pathways.
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| 申请公布号 |
US2010144770(A1) |
申请公布日期 |
2010.06.10 |
| 申请号 |
US20100597271 |
申请日期 |
2010.01.21 |
| 申请人 |
EXELIXIS, INC. |
发明人 |
KOLTUN ELENA S.;KEARNEY PATRICK;AAY NAING;ARCALAS ARLYN;CHAN WAI KI VICKY;CURTIS JEFFRY KIMO;DU HONGWANG;HUANG PING;KANE BRIAN;KIM MOON HWAN;PACK MICHAEL;TSUHAKO AMY L.;XU WEI;ZAHARIA CRISTIANA A.;ZHOU PEIWEN |
| 分类号 |
A61K31/506;A61K31/4439;A61P35/00;C07D239/36;C07D401/10 |
主分类号 |
A61K31/506 |
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