| 摘要 |
<p>Medical product comprises an active substance coating on its surface. The active substance coating comprises at least one separate active substance particles comprising at least one active substance and at least one polymer having a particle diameter = 30 mu m. The active substance particle(s) can be detached from coating of the medical product under physiological conditions in the vascular system, where the detached active substance particle(s) essentially does/do not release the active substance(s) at pH 7.3-7.5. Independent claims are also included for: (1) a method for the production of the medical product, where: at least one separate active substance particles is/are made available; a base body of the medical product is made available; and the base body is coated with the active substance particles in such a manner that the active substance particles can be detached under physiological conditions in the vascular system, in the coated state, but the active substance(s) is/are essentially not released from the detached active substance particles at pH 7.3-7.5; (2) the active substance; and (3) a method for treatment of stenosis, calcified or soft plaque or aneurysm in the vascular system of a human or animal organism comprising: implanting or introducing the active substance coated medical product into the vascular system of human or animal organism. ACTIVITY : Vasotropic. MECHANISM OF ACTION : None given.</p> |
