| 摘要 |
<p>Mixed liquid channel (31) is connected to trapping channel (22) upstream of trap column (23). A mixed liquid of diluent and additive suctioned/emitted by respective liquid feed pumps (35,36) is fed to the mixed liquid channel (31). At the flow of eluate containing a target compound through the trap column (23), the eluate is diluted with the diluent, so that the elution power is lowered to thereby ease trapping of the target compound in the trap column (23). On the other hand, although lowering of the solubility of mobile phase in the eluate would ease precipitation of not only the target compound but also foreign matter, the precipitation can be inhibited by the action of the additive to thereby enable prevention of clogging of the trap column (23) and piping.</p> |
