| 摘要 |
An anti-cancer agent comprising a first component and a second component as active ingredients and is adapted to administer the first component and the second component simultaneously or separately, wherein the first component comprises an isoindolinone derivative represented by formula (I) [wherein R1 and R2 independently represent a hydrogen atom, a substituted or unsubstituted lower alkyl group, -OR4 [wherein R4 represents a hydrogen atom, a substituted or unsubstituted lower alkyl group, or -S(O)2R5 (wherein R5 represents an amino group, a mono- or di-(lower alkylamino) group, a substituted or unsubstituted lower alkyl group, or the like)], or the like; and R3 represents a substituted or unsubstituted lower alkyl group, or the like] or a pharmacologically acceptable salt thereof and the second component is selected from a chemotherapeutic agent, a hormonal therapeutic agent and a molecular targeting agent; and others.
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