| 发明名称 |
1-BENZYL-3-HYDR0XYMETHYLINDAZ0LE DERIVATIVES AND USE THEREOF IN THE TREATMENT OF DISEASES BASED ON THE EXPRESSION OF MCP-1, AND CX3CR1 |
| 摘要 |
The present invention relates to novel 1-benzyl-3-hydroxymethylindazole derivatives according to formula (I) described in the claims, and to a pharmaceutical composition comprising them, together with a pharmaceutically acceptable vehicle. In addition, the present invention relates to the use of novel 1-benzyl-3-hydroxymethylindazole derivatives for the preparation of a pharmaceutical composition that is active in the treatment of diseases based on the expression of MCP-1 and CX3CR1, and to their use in a method for treating or preventing diseases based on the expression of MCP-1 and CX3CR1.
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| 申请公布号 |
WO2009109654(A8) |
申请公布日期 |
2010.06.03 |
| 申请号 |
WO2009EP52660 |
申请日期 |
2009.03.06 |
| 申请人 |
AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A.;GUGLIELMOTTI, ANGELO;FURLOTTI, GUIDO;MANGANO, GIORGINA;CAZZOLLA, NICOLA |
发明人 |
GUGLIELMOTTI, ANGELO;FURLOTTI, GUIDO;MANGANO, GIORGINA;CAZZOLLA, NICOLA |
| 分类号 |
C07D231/54;A61K31/416;A61K31/435;A61P3/10;A61P9/00;A61P13/00;C07D401/12 |
主分类号 |
C07D231/54 |
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