发明名称 |
Compositions for localized therapy of the eye, comprising preferably triamcinolone acetonide and hyaluronic acid |
摘要 |
Compositions, and methods of using such compositions, useful for injection into the posterior segments of human or animal eyes are provided. Such compositions include small particles of a poorly soluble therapeutic agent that facilitates formation of concentrated regions of the therapeutic agent in the retinal pigmented epithelium of an eye. The particles are formed by combining a therapeutic agent with an ophthalmically acceptable polymer component. The particles have sizes less than about 3000 nanometers, and in some cases, less than about 200 nanometers. One example of a composition includes particles of triamcinolone acetonide and hyaluronic acid have a size less than about 3000 nanometers. |
申请公布号 |
AU2005209201(B2) |
申请公布日期 |
2010.06.03 |
申请号 |
AU20050209201 |
申请日期 |
2005.01.14 |
申请人 |
ALLERGAN, INC. |
发明人 |
PATRICK M. HUGHES;SCOTT M. WHITCUP;JAMES A. BURKE;OREST OLEJNIK |
分类号 |
A61K9/00;A61K9/10;A61K9/14;A61K31/00;A61K47/36 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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