摘要 |
<p>The present application is drawn to a synthetic, polymer hydrogel-based material, which is able to actively induce the body's natural hemostatic coagulation process in blood or acellular plasma. The present invention provides the development of a primary amine containing polymer hydrogel capable of inducing blood coagulation and delivering therapeutics for hemostatic or wound care applications, and a method of forming such a primary amine containing polymer hydrogel capable of inducing the blood coagulation process. The primary amine containing polymer hydrogel is able to achieve the same end result as biological-based hemostatics, without the innate risk of disease transmission or immunological response, and at a fraction of the price. Furthermore, due to its inherent hydrogel-based design the material has the capability of arresting blood loss while simultaneously delivering therapeutics in a controlled manner, potentially revolutionizing the way in which wounds are treated.</p> |
申请人 |
UNIVERSITY OF MARYLAND, BALTIMORE;UNIVERSITY OF MARYLAND, COLLEGE PARK;CASEY, BRENDAN, J.;KOFINAS, PETER;BEHRENS, ADAM;SNYDER, TREVOR, A.;GRIFFITH, BARTLEY, P. |
发明人 |
CASEY, BRENDAN, J.;KOFINAS, PETER;BEHRENS, ADAM;SNYDER, TREVOR, A.;GRIFFITH, BARTLEY, P. |