发明名称 MTOR KINASE INHIBITORS FOR ONCOLOGY INDICATIONS AND DISEASES ASSOCIATED WITH THE MTOR/P13K/AKT PATHWAY
摘要 Provided herein are Heteroaryl Compounds having the following structure: R2 N (I) or (II) wherein R1 -R4 are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, neurodegenerative diseases, diabetes, obesity, neurological disorders, age-related diseases, or cardiovascular conditions, comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.
申请公布号 CA2740975(A1) 申请公布日期 2010.06.03
申请号 CA20092740975 申请日期 2009.10.27
申请人 SIGNAL PHARMACEUTICALS, LLC 发明人 ELSNER, JAN;HARRIS, ROY L.;LEE, BRANDEN;MORTENSEN, DEBORAH;PACKARD, GARRICK;PAPA, PATRICK;PERRIN-NINKOVIC, SOPHIE;RIGGS, JENNIFER;SANKAR, SABITA;SAPIENZA, JOHN;SHEVLIN, GRAZIELLA;TEHRANI, LIDA;XU, WEIMING;ZHAO, JINGJING;PARNES, JASON;MADAKAMUTIL, LOUI;FULTZ, KIMBERLY;NARLA, RAMA K.
分类号 C07D487/04;A61K31/4985;A61P35/00 主分类号 C07D487/04
代理机构 代理人
主权项
地址