摘要 |
PROBLEM TO BE SOLVED: To provide a method requiring no high-pressure reactions for simply and safely manufacturing hydroxyalkylpiperazines without using hydrogen having a high risk of inflammation. SOLUTION: The manufacturing method comprises subjecting dihydroxy(alkyl)ethylenediamines represented by formula (1) and the like to an intramolecular dehydration condensation reaction in the presence of an acid catalyst. COPYRIGHT: (C)2010,JPO&INPIT
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