发明名称 |
Plasminogen Activator Inhibitor-1 Inhibitors and Methods of Use Thereof to Modulate Lipid Metabolism |
摘要 |
The invention relates to plasminogen activator-1 (PAI-1) inhibitor compounds and uses thereof in the treatment of any disease or condition associated with elevated PAI-1. The invention includes, but is not limited to, the use of such compounds to modulate lipid metabolism and treat conditions associated with elevated PAI-1, cholesterol, or lipid levels.
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申请公布号 |
US2010137194(A1) |
申请公布日期 |
2010.06.03 |
申请号 |
US20090624126 |
申请日期 |
2009.11.23 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN;EASTERN MICHIGAN UNIVERSITY |
发明人 |
LAWRENCE DANIEL A.;EMAL CORY;CALE JACQUELINE;SU ENMING J.;WARNOCK MARK;LI SHIH-HON;CUPP JEANNE A. |
分类号 |
A61K38/16;A61K31/166;A61K31/235;A61K31/351;A61K31/444;A61K31/4965;A61K31/50;A61K31/5375;A61K31/7028;A61P3/04;A61P3/10;A61P9/04;A61P19/02;A61P25/28;C07C69/76;C07C233/64;C07D237/04;C07D241/04;C07D265/30;C07D311/00;C07D401/12;C07H15/203 |
主分类号 |
A61K38/16 |
代理机构 |
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代理人 |
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地址 |
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