发明名称 |
METHODS AND COMPOSITIONS FOR DETECTION AND ANALYSIS OF POLYNUCLEOTIDES USING LIGHT HARVESTING MULTICHROMOPHORES |
摘要 |
Methods, compositions and articles of manufacture for assaying a sample for a target polynucleotide are provided. A sample suspected of containing the target polynucleotide is contacted with a polycationic multichromophore and a sensor polynucleotide complementary to the target polynucleotide. The sensor polynucleotide comprises a signaling chromophore to receive energy from the excited multichromophore and increase emission in the presence of the target polynucleotide. The methods can be used in multiplex form. Kits comprising reagents for performing such methods are also provided.
|
申请公布号 |
US2010136702(A1) |
申请公布日期 |
2010.06.03 |
申请号 |
US20090632734 |
申请日期 |
2009.12.07 |
申请人 |
|
发明人 |
BAZAN GUILLERMO C.;GAYLORD BRENT S.;WANG SHU |
分类号 |
G01N33/48;C07H21/00;C07H21/02;C07H21/04;C12N;C12Q1/68;G01N21/00;G01N21/64 |
主分类号 |
G01N33/48 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|