<p>The present invention features immunogenic compositions based on pre- fertilization or post-fertilization antigens expressed in the circulating gametocytes in the peripheral blood of infected persons or on the malaria parastes' stages of development in the mosquito midgut including extracellular male and female gametes, fertilized zygote and ookinete. The invention also features methods to prevent the transmission of malaria using the immunogenic compositions of the invention.</p>
申请公布号
WO2010036293(A8)
申请公布日期
2010.06.03
申请号
WO2009US04243
申请日期
2009.07.22
申请人
THE JOHNS HOPKINS UNIVERSITY;THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY;KUMAR, NIRBHAY;ANGOV, EVELINA