IMPROVED METHODS FOR ISOLATING ENVELOPED VIRUS-BASED VLPS FREE OF INFECTIOUS AGENTS
摘要
<p>Enveloped virus-based virus-like particles (VLPs) that are free of infectious agents and substantially as immunogenic as corresponding VLPs prior to inactivation of infectious agents are described. Improved methods of inactivation infectious agents in preparations of enveloped virus-based VLPs are also described wherein the methods do not adversely affect the immunogenicity of the VLPs.</p>
申请公布号
WO2010062757(A1)
申请公布日期
2010.06.03
申请号
WO2009US63128
申请日期
2009.11.03
申请人
LIGOCYTE PHARMACEUTICALS, INC.;HAYNES, JOEL, R.;TAYLOR, ROSS