发明名称 |
METHOD FOR PRODUCTION OF 3-HYDROXYPROPAN-1-ONE COMPOUND FOR PRODUCTION OF 2- PROPEN-1-ONE COMPOUND AND METHOD FOR PRODUCTION OF ISOXAZLINE COMPOUND |
摘要 |
There is provided a novel intermediate for producing pesticides. A method for producing 1,3-bis(substituted phenyl)-3-substituted-3-hydroxypropan-1-one compound of Formula (3) comprises reacting an aromatic ketone compound of Formula (4) and a substituted acetophenone compound of Formula (5) as starting raw materials in an organic solvent or water in the presence or absence of an additive in the presence of a base in a suspended state. A method for producing 1,3-bis(substituted phenyl)-3-substituted-2-propen-2-one compound of Formula (2) comprises dehydrating the compound of Formula (3). A method for producing compound (2) in one step comprises reacting compound (4) and compound (5) to obtain compound (3). Further, a method for producing an isoxazoline compound of Formula (1) comprises reacting compound (2) and a hydroxylamine in an aliphatic or an aromatic hydrocarbon solvent which is optionally substituted by a halogen atom by adding an additive selected from a phase-transfer catalyst, a C1-C6 alcohol and an aprotic polar solvent in the presence of a base and water.
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申请公布号 |
US2010137612(A1) |
申请公布日期 |
2010.06.03 |
申请号 |
US20080452347 |
申请日期 |
2008.06.27 |
申请人 |
NISSAN CHEMICAL INDUSTRIES, LTD. |
发明人 |
YAOSAKA MANABU;UTSUNOMIYA TOMOHISA;MORIYAMA YUJI;MATSUMOTO TOMOHIRO;MATOBA KAZUTAKA |
分类号 |
C07D261/04;C07C45/61;C07C63/06 |
主分类号 |
C07D261/04 |
代理机构 |
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主权项 |
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