VACCINE COMPOSITION AGAINT EQUINE HERPESVIRUS FOR TARGETING FC RECEPTOR OF DENDRITIC CELLS

摘要

PURPOSE: A horse herpesvirus vaccine formulation targeting Fc receptor of dendritic cells is provided to effectively enhance horse immunity. CONSTITUTION: An EHV-1(equine Herpesvirus-1) vaccine formulation contains a fusion protein as an active ingredient, in which inactivated EHV-1 and immunoglobulin heavy chain constant region are conjugated by covalent bond. The inactivated EHV-1 is obtained using ethylene imine, derivative of ethylene imine, beta-propiolactone, aldehyde compound, formalin, phenol, hypochlorite, or detergent. The EHV-1 vaccine formulation additionally contains an adjuvant. The vaccine formulation is used for injection.