发明名称 |
JAK-2 Modulators and Methods of Use |
摘要 |
This invention relates to the field of protein tyrosine kinases and inhibitors thereof. In particular, the invention relates to inhibitors of JAK-2, pharmaceutical compositions of the compounds for inhibiting JAK-2, methods of inhibiting JAK-2 in a cell, comprising contacting a cell in which inhibition of JAK-2 is desired with a compound or pharmaceutical composition comprising a compound according to the invention. The also comprises methods of treating a disease or condition that involves JAK-2 comprising administering to a patient a pharmaceutical composition comprising a compound according to the invention.
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申请公布号 |
US2010136136(A1) |
申请公布日期 |
2010.06.03 |
申请号 |
US20070443103 |
申请日期 |
2007.09.28 |
申请人 |
EXELIXIS, INC. |
发明人 |
GALAN ADAM ANTONI;CHEN JEFF;DU HONGWANG;FORSYTH TIMOTHY;HUYNH TAI PHAT;JOHNSON HENRY WILLIAM BEECROFT;KEARNEY PATRICK;LEAHY JAMES W.;LEE MATTHEW SANGYUP;MANN GRACE;RIDGWAY BRIAN HUGH;TAKEUCHI CRAIG STACY;ZHOU PEIWEN |
分类号 |
A61K31/4178;A61K31/4184;A61K31/437;A61K31/4439;A61K31/454;A61K31/496;A61K31/5377;A61K31/704;A61K31/7076;A61K33/24;A61P35/00;C07D401/14;C07D403/12;C07D403/14;C07D413/14;C12N5/00 |
主分类号 |
A61K31/4178 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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