发明名称 |
FREQUENCY-SHIFT CMOS MAGNETIC BIOSENSOR ARRAY WITH SINGLE BEAD SENSITIVITY AND NO EXTERNAL MAGNET |
摘要 |
According to one aspect, an integrated magnetic particle measurement device for detecting a presence or absence of magnetic particles in a sample volume includes at least one sensor cell having a differential sensor pair. An active sensor oscillator frequency is responsive to one or more magnetic particles situated within a sample volume. The sensor cell is configured to be operative in the absence of an externally applied magnetic field. A frequency measurement circuit provides as a time-multiplexed output a first count representative of the active sensor oscillator frequency and a second count representative of the reference sensor oscillator frequency. A calculated difference between the first count and the second count is indicative of a presence or an absence of one or more magnetic particles within the sample volume. An integrated magnetic particle measurement system array and a method for detecting one or more magnetic particles are also described.
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申请公布号 |
US2010134097(A1) |
申请公布日期 |
2010.06.03 |
申请号 |
US20090559517 |
申请日期 |
2009.09.15 |
申请人 |
CALIFORNIA INSTITUTE OF TECHNOLOGY |
发明人 |
WANG HUA;HAJIMIRI SEYED ALI |
分类号 |
G01R33/12 |
主分类号 |
G01R33/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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