ORALLY RAPIDLY DISINTEGRATING TABLET, AND PROCESS FOR PRODUCING SAME

摘要

Disclosed is an orally rapidly disintegrating tablet characterized in that the tablet can be produced in a conventional tablet production facility and has a satisfactory level of hardness for practical applications, and the change in properties of the tablet (i.e., decreased in hardness of the tablet, and delay of the time required for disintegration of the tablet in the oral cavity) are rarely caused by factors such as humidity.  The orally rapidly disintegrating tablet has hardness of 40 N or more, can be disintegrated in the oral cavity within 60 seconds, and is produced by compression molding of a mixture of (a) an active ingredient, (b) an excipient having good water wettability, (c) a water-insoluble polymer that has good moldability and does not substantially cause the decrease in the water wettability of the excipient and (d) a disintegrating agent.