发明名称 |
DIAGNOSIS, PROGNOSIS AND MONITORING OF DISEASE PROGRESSION OF SYSTEMIC LUPUS ERYTHEMATOSUS THROUGH BLOOD LEUKOCYTE MICROARRAY ANALYSIS |
摘要 |
<p>The present invention includes an apparatus, system and method for the development and use of transcriptional modules by obtaining individual gene expression levels from cells obtained from one or more patients with a disease or condition; recording the expression value for each gene in a table that is divided into clusters; iteratively selecting gene expression values for one or more transcriptional modules by: selecting for the module the genes from each cluster that match in every disease or condition; removing the selected genes from the analysis; and repeating the process of gene expression value selection for genes that cluster in a sub-fraction of the diseases or conditions; and iteratively repeating the generation of modules.</p> |
申请公布号 |
EP1968610(A4) |
申请公布日期 |
2010.06.02 |
申请号 |
EP20060839208 |
申请日期 |
2006.12.09 |
申请人 |
BAYLOR RESEARCH INSTITUTE |
发明人 |
CHAUSSABEL, DAMIEN;BANCHEREAU, JACQUES, F. |
分类号 |
G06F19/00;C12Q1/68 |
主分类号 |
G06F19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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