发明名称 |
Adamantyl-pyrazole carboxamides as inhibitors of 11β-hdroxysteroid dehydrogenase |
摘要 |
Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, type II diabetes mellitus and metabolic syndrome.
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申请公布号 |
US7728029(B2) |
申请公布日期 |
2010.06.01 |
申请号 |
US20070717996 |
申请日期 |
2007.03.14 |
申请人 |
HOFFMANN-LA ROCHE INC. |
发明人 |
ANDERSON KEVIN WILLIAM;FOTOUHI NADER;GILLESPIE PAUL;GOODNOW, JR. ROBERT ALAN;GUERTIN KEVIN RICHARD;HAYNES NANCY-ELLEN;MYERS MICHAEL PAUL;PIETRANICO-COLE SHERRIE LYNN;QI LIDA;ROSSMAN PAMELA LOREEN;SCOTT NATHAN ROBERT;THAKKAR KSHITIJ CHHABILBHAI;TILLEY JEFFERSON WRIGHT;ZHANG QIANG |
分类号 |
A61K31/4155;A61K31/415;A61K31/454;A61K31/5377;C07D231/14;C07D401/04;C07D403/04;C07D413/04 |
主分类号 |
A61K31/4155 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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