发明名称 |
PROCESS FOR THE PREPARATION OF THE POLYMORPH A OF DOXAZOSIN MESYLATE |
摘要 |
The invention discloses a process for the preparation of the polymorph A of doxazosin mesylate, consisting essentially of reacting doxazosin base with methanesulfonic acid in a mixture of solvents containing an alcohol and a chlorinated solvent, subsequently removing the chlorinated solvent by distillation and precipitating the desired product in an alcohol, after heating the suspension formed to the reflux temperature of the solvent.
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申请公布号 |
CA2367671(C) |
申请公布日期 |
2010.06.01 |
申请号 |
CA20002367671 |
申请日期 |
2000.03.13 |
申请人 |
MEDICHEM, S.A. |
发明人 |
ARNALOT I AGUILAR, CARMEN;BOSCH I LLADO, JORDI;ONRUBIA MIGUEL, MA CARMEN |
分类号 |
C07D405/12;C07D239/95;C07D319/20 |
主分类号 |
C07D405/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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