| 发明名称 |
PLASMODIUM FALCIPARUM AMA-1 PROTEIN AND USES THEREOF |
| 摘要 |
In this application is described the expression and purification of a recombinant Plasmodium falciparum (3D7) AMA-1 ectodomain. The method of the present invention produces a highly purified protein which retains folding and disulfide bridging of the native molecule. The recombinant AMA-1 is useful as a diagnostic reagent, for use in antibody production, and as a vaccine.
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| 申请公布号 |
CA2441952(C) |
申请公布日期 |
2010.06.01 |
| 申请号 |
CA20022441952 |
申请日期 |
2002.03.25 |
| 申请人 |
WALTER REED ARMY INSTITUTE OF RESEARCH |
发明人 |
LANAR, DAVID E.;DUTTA, SHEETIJ;WARE, LISA A.;NAIR, LALITHA P. V. |
| 分类号 |
C12N15/30;A61K39/00;A61K39/015;A61P33/02;C07K14/445;C07K16/20;C12P21/02;C12P21/04;G01N33/569 |
主分类号 |
C12N15/30 |
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