发明名称 EML4-ALK fusion gene
摘要 The present inventors found that a fusion gene present in some cancer patients is an oncogene. The present invention relates to a polypeptide as a novel fusion protein, a polynucleotide encoding the polypeptide, a vector comprising the polynucleotide, a transformed cell comprising the vector, a method for detecting the fusion protein or polynucleotide, a method for screening a therapeutic agent for cancer, and a method for treating cancer that is shown to be positive for the fusion gene. Further, the present invention relates kit, primer set, and probe useful in the detection of cancer that is shown to be positive for the fusion gene.
申请公布号 US7728120(B2) 申请公布日期 2010.06.01
申请号 US20070845498 申请日期 2007.08.27
申请人 ASTELLAS PHARMA INC.;CUREGENE K.K. 发明人 MANO HIROYUKI;KUROMITSU SADAO;SHINDO NOBUAKI;SOGA TAKATOSHI;FURUTANI TAKASHI
分类号 C07H21/04 主分类号 C07H21/04
代理机构 代理人
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