| 发明名称 |
Macrocyclic compounds useful as pharmaceuticals |
| 摘要 |
The present invention provides compounds having formula (I), and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of various disorders including inflammatory or autoimmune disorders, and disorders involving malignancy or increased angiogenesis, wherein R 1 -R 11 , t, X, Y, Z and n are as defined herein. |
| 申请公布号 |
AU2010201776(A1) |
申请公布日期 |
2010.05.27 |
| 申请号 |
AU20100201776 |
申请日期 |
2010.05.04 |
| 申请人 |
EISAI R&D MANAGEMENT CO., LTD. |
发明人 |
JEAN-CHRISTOPHE HARMANGE;HIROSHI SHIROTA;ISAO TANAKA;KENZO MURAMOTO;YOSHIKAZU KUBOI;HONG DU;CHARLES-ANDRE LEMELIN;YONG-CHUN SHEN;AKIFUMI KIMURA;ROCH BOIVIN;MARK SPYVEE;MEGUMI KAWADA;JOHN (YUAN) WANG;MASANORI FUJITA;FABIAN GUSOVSKY;TAKATOSHI KAWAI;HIDEKI SUKURAI;YOSHIHITO EGUCHI;MASAKI GOTO;YOSHIYUKI KAWAKAMI;YOSHIHARU MIZUI;SATOSHI YAMAMOTO;YIMIN JIANG;TOMOHIRO MATSUSHIMA;XIANG-YI LI;NAOKI YONEDA;JESSE CHOW;ATSUSHI INOUE;MAKOTO KOTAKE;KENICHI CHIBA |
| 分类号 |
C07D491/044;A61K31/335;A61K31/36;A61K31/365;A61K31/395;A61K31/4178;A61K31/4188;A61K31/5377;A61P1/00;A61P1/04;A61P1/16;A61P3/10;A61P7/04;A61P9/00;A61P9/10;A61P11/00;A61P11/02;A61P11/06;A61P17/00;A61P17/04;A61P17/06;A61P17/16;A61P19/02;A61P19/04;A61P19/10;A61P21/04;A61P25/00;A61P25/02;A61P25/08;A61P25/28;A61P27/02;A61P29/00;A61P31/04;A61P31/18;A61P33/06;A61P35/00;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07D267/00;C07D313/00;C07D401/12;C07D405/12;C07D491/04;C07D493/04;C07D521/00 |
主分类号 |
C07D491/044 |
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