MEMS CHIP FOR CHROMATIN IMMUNOPRECIPITATION (ChIP) AND CHIP METHOD USING SAME

摘要

The present invention relates to an MEMS chip for chromatin immunoprecipitation (ChIP) which replaces conventional EP tubes used for ChIP experiments and which performs ChIP experiments, and to a ChIP method using same. The MEMS chip for ChIP comprises: an injection port through which a sample including a protein that is bound with DNA and antibody is introduced; a chamber communicated with the injection port, and having a plurality of beads positioned on the inner surface thereof, wherein a specific protein that binds with the antibody is fixed to the beads; and a discharge port communicated with the chamber, and formed on the other side of the injection port so as to discharge the introduced sample. Accordingly, the MEMS chip of ChIP can replace the conventional ChIP technology that uses EP tubes, and thus can carry out experiments with a small quantity of sample, with less amount of experimentation time, and have less fluctuation in experimental results, and also can carry out ChIP experiments even at room temperature.