发明名称 |
METHODS AND COMPOSITIONS IN PARTICLE-BASED DETECTION OF TARGET MOLECULES USING LINKING MOLECULES |
摘要 |
Methods and compositions which can be used to increase the strength and/or probability of forming a binding complex comprising a target molecule and a substrate are disclosed. In one aspect, linking molecules are disclosed which can be used to increase the number of intra-complex binding interactions. Covalent bonds can be introduced to further increase the strength of these binding interactions. Inter-complex cross-linking can be utilized in connection with these methods to further strengthen and stabilize the disclosed binding complexes. |
申请公布号 |
US2010129819(A1) |
申请公布日期 |
2010.05.27 |
申请号 |
US20090612203 |
申请日期 |
2009.11.04 |
申请人 |
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发明人 |
HU CELINE;XU JIANPING;GAO HETIAN;PERKINS JULIE |
分类号 |
C12Q1/68;C07H21/04;C12P19/34 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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