摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method for producing a 2-aryl-2,2-difluoroacetic acid ester. Ž<P>SOLUTION: This 2-aryl-2,2-difluoroacetic acid ester useful as a production intermediate of a medicine, an agrochemical and a functional material can be produced by efficiently progressing the coupling reaction of a zinc reagent with 2-bromo-2,2-difluoroacetic acid ester in the presence of a cobalt catalyst and a diamine-based ligand. Ž<P>COPYRIGHT: (C)2010,JPO&INPIT Ž
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