| 发明名称 |
REGULATION OF CELL SURVIVAL BY HSP90 AND IP6K2 |
| 摘要 |
Anti-cancer drugs are identified by screening for agents and compounds which inhibit the binding of HSP90 and IP6K2. In vitro and in vivo assays can be used. Any phenomenon associated with the binding or inhibition can be monitored, including cell death, subcellular localization, catalytic activity of IP6K2, and IP7 formation.
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| 申请公布号 |
US2010129806(A1) |
申请公布日期 |
2010.05.27 |
| 申请号 |
US20070514254 |
申请日期 |
2007.12.11 |
| 申请人 |
THE JOHNS HOPKINS UNIVERSITY |
发明人 |
SNYDER SOLOMON H.;CHAKRABORTY ANUTOSH;KOLDOBSKIY MICHAEL;SIXT KATHERINE;JULURI KRISHNA;MUSTAFA ASIF K.;VAN ROSSUM DAMIAN B.;PATTERSON RANDEN L. |
| 分类号 |
C12Q1/68;C07K14/00;C12N5/00;G01N30/00;G01N33/53 |
主分类号 |
C12Q1/68 |
| 代理机构 |
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